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immunosuppressant used in tissue transplants. It prevents graft rejection by the host's immune system. It is very important to monitor its level. Too little of this drug will cause graft rejection, while too much will lead to infection. This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes. The mmycophenylate blood test is usually measured as a “trough” level, that is, the blood sample is taken just before the next dose of the medicine is due, when the drug is at its lowest concentration in the blood. Monitoring therapy to ensure adequate blood levels and avoid over-immunosuppression Feb 21, 2019 · Identifying no clinically significant laboratory changes, this analysis suggests that routine laboratory monitoring for patients on mycophenolate for dermatologic use is unnecessary. Jan 29, 2019 · What is being tested? This test measures the amount of mycophenolic acid in the blood. Mycophenolic acid is the active metabolite of mycophenolate, a drug that is usually given to patients who have had a heart, kidney, or liver transplant to help prevent rejection. Jul 15, 2019 · Learn in-depth information on Mycophenolic Acid Blood Test, on why the laboratory test is performed, specimen collected, the significance of the results, and its use in diagnosing medical conditions. Monitoring of mycophenolic acid (MPA) levels may be useful for effective mycophenolate mofetil (MMF) dosing. However, whether commonly obtained trough levels are an acceptable method of surveillance remains debatable. The concentration-effect relationship for mycophenolic acid (MPA), and the high variability in MPA concentrations in patients on standard dose mycophe- nolate mofetil (MMF) therapy, for some centers has provided enough evidence to implement therapeutic drug monitoring (TDM) for MMF

in daily practice.